EVA-MARIA STRAUCH, Ph.D.
Pharmaceutical and Biomedical Sciences
Assistant Professor
Pharmaceutical and Biomedical Sciences
Pharmaceutical and Biomedical Sciences
2002- 2007 Ph.D. in Biochemistry, University of Texas at Austin; Austin, Texas
2005 M.A. in Biochemistry, University of Texas at Austin; Austin, Texas
2001 B.Sc. equivalent, Julius-Maximilians Universität, Würzburg major: Biochemistry, minor: Microbiology, Genetics and Biotechnology
Research Area: Protein design and engineering, design of anti-virals and immunogens, immunoinformatics, protein chemistry and re-purposing of viral surface proteins, computational biology
Opportunities for collaborations: Vaccine design, protein-based therapeutics, protein mediated drug delivery
2017 Foresight Fellow for catalyzing future technology (Foresight Institute)
2009 – 2012 Career Development Award, NW Regional Center of Excellence (NIAID/NIH)
Jun. 2007 Professional Development Award, Dept. of Chemistry and Biochemistry, UT Austin
Jan. 2007 Travel Award for the “SBE’s First International Conference on Biomolecular Engineering”
Sep. 2006 Stipend for NIH National Graduate Student Research Festival
Apr. 2006 Joanne Ravel Award, Dept. of Chemistry and Biochemistry, UT Austin
American Association for the Advancement of Science (Member)
We are a new lab using computational structural design and protein engineering tools to understand, inhibit and re-purpose biological processes on the protein level. Our main focus is on how to diagnose, prevent and treat viral infections with the aim to generate new anti-virals and candidates for vaccination. While we are studying viral surface proteins principally to understand how we can target them or provide new immunogens, we also seek to shed light on how protein chemistry is involved in making viruses so successful. Viruses and their surface proteins hold the molecular keys for identifying specific host cells, entering them and re-programming them–much of what we will need to fight cancer.
Strauch EM, Bernard S, La D, Bohn A, Nieusma T, Lee P, Garcia NK, Holstein C, Anderson CE, Hooper KA, Trenant M, Sheffler W, Bloom JD, Yager P, Lee KK, Ward A, Fuller D, Wilson IA, Baker D, “Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site”, Nat Biotechnol. 2017 Jul;35(7):667-671. doi: 10.1038/nbt.3907
Special reports in:
Holstein CA*, Anderson CE*, Strauch EM, Bennett S, Chevalier A, Nelson J, Fu E, Baker D, Yager P; Development of a Paper-Based Assay for Whole Influenza Virus Detection using a Computationally Designed Hemagglutinin Head Region Binder, Anal Chem. 2017 Jun 20;89(12):6608-6615. doi: 10.1021/acs.analchem.7b00769
Klein JC, Lajoie MJ, Schwartz JJ, Strauch EM, Nelson J, Baker B, Shendure J, “Multiplex pairwise assembly of array-derived DNA oligonucleotides”, Nucleic Acids Res. 2016 Mar 18;44(5):e43. doi: 10.1093
Strauch EM, Fleishman SJ, Baker D, ” Computational Design of a pH-sensitive IgG Binding Protein”, Proc Natl Acad Sci U S A., 2014 Jan 14;111(2):675-80, PMID: 24381156
* = contributed equally
Office: 706-542-7725
Email: estrauch@uga.edu
Campus Address
Pharmacy South, Rm 324
Ranked in the top 24 of pharmacy programs in the country by US News & World Report, UGA Pharmacy is at the top of its class. Learn more below:
The University of Georgia
College of Pharmacy
250 W. Green Street
Athens, Georgia 30602
Phone: (706) 542-1911
Fax: (706) 542-5269