Maria Luisa Valle, Yasmin Tarek Anderson, Neil Grimey, and Jason Zastre. Thiamine Insufficiency induces Hypoxia Inducible Factor-1a as an upstream mediator for neurotoxicity and AD-like pathology. Molecular and Cellular Neuroscience. 2022. 123:103785
Jonus HC, Byrnes CC, Kim J, Valle ML, Bartlett MG, Said HM, Zastre JA. Thiamine mimetics sulbutiamine and benfotiamine as a nutraceutical approach to anticancer therapy. Biomed Pharmacother. 2020 Jan; 121
Kim J, Jonus HC, Zastre JA, Bartlett MG. Development of an IPRP-LC-MS/MS method to determine the fate of intracellular thiamine in cancer cells. J Chromatogr B Analyt Technol Biomed Life Sci. 2019 Aug 15;1124:247-255
Jonus HC, Hanberry BS, Khatu S, Kim J, Luesch H, Dang LH, Bartlett MG, Zastre JA. The adaptive regulation of thiamine pyrophosphokinase-1 facilitates malignant growth during supplemental thiamine conditions. Oncotarget, 2018. 9 (83):35422-35438.
Zera, K. and J. Zastre (2018). Stabilization of the hypoxia-inducible factor-1 alpha in thiamine deficiency is mediated by pyruvate accumulation. Toxicol Appl Pharmacol.355:180-188.
Zera and J. Zastre. Thiamine deficiency activates hypoxia inducible factor-1alpha to facilitate pro-apoptotic responses in mouse primary astrocytes. Plos One. 12 (10): e0186707 (2017).